Cart
sales@molnova.com
sphondin
CAS No. 483-66-9
sphondin( —— )
Catalog No. M20453 CAS No. 483-66-9
Sphondin has anticonvulsant anti-inflammatory and anti-proliferative activities it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 224 | In Stock |
|
| 5MG | 250 | In Stock |
|
| 10MG | 392 | In Stock |
|
| 25MG | 639 | In Stock |
|
| 50MG | 873 | In Stock |
|
| 100MG | 1172 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Namesphondin
-
NoteResearch use only, not for human use.
-
Brief DescriptionSphondin has anticonvulsant anti-inflammatory and anti-proliferative activities it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.
-
DescriptionSphondin has anticonvulsant anti-inflammatory and anti-proliferative activities it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.
-
In VitroPretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE2 release.
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetCOX
-
RecptorCOX-2|PGE2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number483-66-9
-
Formula Weight216.19
-
Molecular FormulaC12H8O4?
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 25 mg/mL (115.64 mM)
-
SMILESCOc1cc2ccc(=O)oc2c2ccoc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Yang L L Liang Y C Chang C W et al. Effects of sphondin isolated from Heracleum laciniatum on IL–1β-induced cyclooxygenase-2 expression in human pulmonary epithelial cells[J]. Life Sciences 2002 72(2):199-213.
molnova catalog
related products
-
Nepodin
Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity.
-
Indomethacin heptyl ...
Indomethacin heptyl ester is a non-selective inhibitor of both COX-1 and COX-2
-
Asperosaponin Ⅵ
Asperosaponin Ⅵ is extracted from Dipsacus asperoides.
