Cart
sales@molnova.com
TRPM8 antagonist 2
CAS No. 259674-19-6
TRPM8 antagonist 2( —— )
Catalog No. M20423 CAS No. 259674-19-6
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
|
| 5MG | 61 | In Stock |
|
| 10MG | 101 | In Stock |
|
| 25MG | 170 | In Stock |
|
| 50MG | 269 | In Stock |
|
| 100MG | 431 | In Stock |
|
| 200MG | 619 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTRPM8 antagonist 2
-
NoteResearch use only, not for human use.
-
Brief DescriptionTRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.
-
DescriptionTRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetTRP/TRPV Channel
-
RecptorTRPM8
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number259674-19-6
-
Formula Weight398.5
-
Molecular FormulaC26H26N2O2?
-
Purity>98% (HPLC)
-
SolubilityDMSO:160 mg/mL (401.51 mM)
-
SMILESCOC(=O)[C@H](Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Alessia B Nunzio I Carmine O et al. Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity[J]. Journal of Medicinal Chemistry 2018:acs.jmedchem.8b00545-.
molnova catalog
related products
-
n-Butylidenephthalid...
(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
-
AMG2850
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).
-
RN9893
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.
