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TRPM8 antagonist 2

CAS No. 259674-19-6

TRPM8 antagonist 2( —— )

Catalog No. M20423 CAS No. 259674-19-6

TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 67 In Stock
5MG 61 In Stock
10MG 101 In Stock
25MG 170 In Stock
50MG 269 In Stock
100MG 431 In Stock
200MG 619 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    TRPM8 antagonist 2
  • Note
    Research use only, not for human use.
  • Brief Description
    TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.
  • Description
    TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM used in the research of neuropathic pain syndromes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    TRPM8
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    259674-19-6
  • Formula Weight
    398.5
  • Molecular Formula
    C26H26N2O2?
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:160 mg/mL (401.51 mM)
  • SMILES
    COC(=O)[C@H](Cc1c[nH]c2ccccc12)N(Cc1ccccc1)Cc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Alessia B Nunzio I Carmine O et al. Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity[J]. Journal of Medicinal Chemistry 2018:acs.jmedchem.8b00545-.
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