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marmesin
CAS No. 13849-08-6
marmesin( (+)-Marmesin | (S)-Marmesin )
Catalog No. M20394 CAS No. 13849-08-6
Marmesin is a coumarin originally isolated from the mature bark of A. marmelosexhibiting COX-2/5-LOX dual inhibitory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 58 | In Stock |
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| 10MG | 87 | In Stock |
|
| 25MG | 177 | In Stock |
|
| 50MG | 290 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product Namemarmesin
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NoteResearch use only, not for human use.
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Brief DescriptionMarmesin is a coumarin originally isolated from the mature bark of A. marmelosexhibiting COX-2/5-LOX dual inhibitory activity.
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DescriptionMarmesin is a coumarin originally isolated from the mature bark of A. marmelosexhibiting COX-2/5-LOX dual inhibitory activity.
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In VitroS-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity.
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In Vivo——
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Synonyms(+)-Marmesin | (S)-Marmesin
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PathwayImmunology/Inflammation
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TargetLipoxygenase
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Recptor5-Lipoxygenase|COX-2
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Research Area——
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Indication——
Chemical Information
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CAS Number13849-08-6
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Formula Weight246.26
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Molecular FormulaC14H14O4
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Purity>98% (HPLC)
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SolubilityDMSO:2 mg/mL (8.12 mM)
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SMILESCC(C)(O)[C@@H]1Cc2cc3ccc(=O)oc3cc2O1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Marmesin is a novel angiogenesis inhibitor: Regulatory effect and molecular mechanism on endothelial cell fate and angiogenesis[J]. Cancer Letters 2015 369(2):323-330.
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