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Dimethylfraxetin
CAS No. 6035-49-0
Dimethylfraxetin( 678-Trimethoxycoumarin | Fraxetin dimethyl ether )
Catalog No. M20278 CAS No. 6035-49-0
Dimethylfraxetin is a Carbonic anhydrase inhibitor（Ki：0.0097 μM）
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 89 | In Stock |
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| 5MG | 72 | In Stock |
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| 10MG | 129 | In Stock |
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| 25MG | 259 | In Stock |
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| 50MG | 365 | In Stock |
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| 100MG | 514 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDimethylfraxetin
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NoteResearch use only, not for human use.
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Brief DescriptionDimethylfraxetin is a Carbonic anhydrase inhibitor（Ki：0.0097 μM）
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DescriptionDimethylfraxetin is a Carbonic anhydrase inhibitor.（Ki：0.0097 μM）.
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In VitroAt CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study.
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In Vivo——
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Synonyms678-Trimethoxycoumarin | Fraxetin dimethyl ether
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PathwayMembrane Transporter/Ion Channel
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TargetCarbonic Anhydrase
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RecptorCarbonic Anhydrase
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Research Area——
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Indication——
Chemical Information
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CAS Number6035-49-0
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Formula Weight236.22
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Molecular FormulaC12H12O5
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL?(529.17 mM)
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SMILESCOc1cc2ccc(=O)oc2c(OC)c1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Davis R A Vullo D Maresca A et al. Natural product coumarins that inhibit human carbonic anhydrases[J]. Bioorganic & medicinal chemistry 2012 21(6):1539-1543.
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