5a-Pregnane-320-dione

CAS No. 566-65-4

5a-Pregnane-320-dione( —— )

Catalog No. M20274 CAS No. 566-65-4

5a-Pregnane-320-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
100MG 27 In Stock
200MG Get Quote In Stock
500MG 56 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    5a-Pregnane-320-dione
  • Note
    Research use only, not for human use.
  • Brief Description
    5a-Pregnane-320-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone
  • Description
    5a-Pregnane-320-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone.
  • In Vitro
    5a-Pregnane-3,20-dione decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    566-65-4
  • Formula Weight
    316.48
  • Molecular Formula
    C21H32O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:5 mg/mL (15.80 mM; Need ultrasonic and warming)
  • SMILES
    [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wiebe J P Muzia D . The endogenous progesterone metabolite 5a-pregnane-320-dione decreases cell-substrate attachment adhesion plaques vinculin expression and polymerized F-actin in MCF-7 breast cancer cells.[J]. Endocrine 2001 16(1):7-14.
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