5a-Pregnane-320-dione( —— )

Catalog No. M20274 CAS No. 566-65-4

5a-Pregnane-320-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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500MG	67	In Stock
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Biological Information

Product Name

5a-Pregnane-320-dione
Note

Research use only, not for human use.
Brief Description

5a-Pregnane-320-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone
Description

5a-Pregnane-320-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone.
In Vitro

5a-Pregnane-3,20-dione decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerizes F-actin in MCF-7 breast cancer cells.
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Human Endogenous Metabolite
Research Area

——
Indication

——

Chemical Information

CAS Number

566-65-4
Formula Weight

316.48
Molecular Formula

C21H32O2
Purity

>98% (HPLC)
Solubility

DMSO:5 mg/mL (15.80 mM; Need ultrasonic and warming)
SMILES

[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Wiebe J P Muzia D . The endogenous progesterone metabolite 5a-pregnane-320-dione decreases cell-substrate attachment adhesion plaques vinculin expression and polymerized F-actin in MCF-7 breast cancer cells.[J]. Endocrine 2001 16(1):7-14.

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