GSK963 (Racemate)( —— )

Catalog No. M20223 CAS No. 2049868-46-2

GSK963 (Racemate) a structurally distinct potent and selective inhibitor of RIP1 kinase(IC50=29 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	39	Get Quote
5MG	65	Get Quote
10MG	110	Get Quote
25MG	222	Get Quote
50MG	357	Get Quote
100MG	524	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

GSK963 (Racemate)
Note

Research use only, not for human use.
Brief Description

GSK963 (Racemate) a structurally distinct potent and selective inhibitor of RIP1 kinase(IC50=29 nM).
Description

GSK963 (Racemate) a structurally distinct potent and selective inhibitor of RIP1 kinase(IC50=29 nM).
In Vitro

——
In Vivo

Animal Model:C57BL/6 mice.Dosage:0.2 mg/kg, 2 mg/kg, 10?mg/kg.Administration:IP once.Result:Protected mice from TNF+zVAD-induced hypothermia.
Synonyms

——
Pathway

Apoptosis
Target

TNF
Recptor

RIP1
Research Area

——
Indication

——

Chemical Information

CAS Number

2049868-46-2
Formula Weight

230.31
Molecular Formula

C14H18N2O?
Purity

>98% (HPLC)
Solubility

DMSO:40 mg/mL (173.67 mM)
SMILES

CC(C)(C)C(=O)N1N=CCC1c1ccccc1
Chemical Name

22-Dimethyl-1-(5(S)-phenyl-45-dihydro-pyrazol-1-yl)-propan-1-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Berger SB et al. Characterization of GSK'963: a structurally distinct potent and selective inhibitor of RIP1 kinase. Cell Death Discov. 2015 Jul 27;1:15009.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks