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N-Succinimidyl 4-(N-maleimidomethyl)cycl

CAS No. 64987-85-5

N-Succinimidyl 4-(N-maleimidomethyl)cycl( —— )

Catalog No. M20183 CAS No. 64987-85-5

N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC) also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate is a heterobifunctional protein crosslinker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-Succinimidyl 4-(N-maleimidomethyl)cycl
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC) also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate is a heterobifunctional protein crosslinker.
  • Description
    N-Succinimidyl 4-(N-maleimidomethyl)cycl(SMCC) also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate is a heterobifunctional protein crosslinker.
  • In Vitro
    SMCC or sulfo-SMCC can use to conjugate keyhole limpet hemocyanin (KLH) and ovalbumin (OVA). In the the conjugation system, 300 μl KLH or OVA (3 mg) and 30 μl SMCC or Sulfo-SMCC (the final concentration of 0.1 mM) are added in PBS with final volume of 3 ml.
  • In Vivo
    Using the SMCC-conjugation method is able to induce potent immune responses to whole protein or peptide antigens by injection of antigen-coupled syngeneic splenic mononuclear cells in mice.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    64987-85-5
  • Formula Weight
    334.32
  • Molecular Formula
    C16H18N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1
  • Chemical Name
    N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li F Wang Z Huang Y Xu H He L Deng Yan Zeng X He N. Delivery of PUMA Apoptosis Gene Using Polyethyleneimine-SMCC-TAT/DNA Nanoparticles: Biophysical Characterization and In Vitro Transfection Into Malignant Melanoma Cells. J Biomed Nanotechnol. 2015 Oct;11(10):1776-82. PubMed PMID: 26502640.
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