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VK3-OCH3
CAS No. 255906-59-3
VK3-OCH3( 2-[(2-Methoxy)ethylthio]-3-methyl-14-na )
Catalog No. M20174 CAS No. 255906-59-3
2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 81 | In Stock |
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| 10MG | 113 | In Stock |
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| 25MG | 200 | In Stock |
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| 50MG | 291 | In Stock |
|
| 100MG | 416 | In Stock |
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| 200MG | 588 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameVK3-OCH3
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NoteResearch use only, not for human use.
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Brief Description2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
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Description2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
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In VitroVK3-OCH3 (compound 5) shows cytotoxicity with IC50s of 2.43, 1.55, 10.69, 3.45, 26.24, 87.11 μM for IMR-32, LA-N-1, NB-39, SK-N-SH, HUVEC, HDF cells, respectively.VK3-OCH3 (1, 3, 10 μM) induces apoptosis and cell cycle arrest at G2/M phase in IMR-32 cells.VK3-OCH3 (0-48 h) increases the expression of HO-1 in 8~24 h, and Caveolin-1 in 48 h in IMR-32 and LA-N-1 cells.VK3-OCH3 (0-48 h) increases the expression of phospho-p38-MAPK and decreases the expression of p21 and clusterin.
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In Vivo——
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Synonyms2-[(2-Methoxy)ethylthio]-3-methyl-14-na
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number255906-59-3
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Formula Weight262.32
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Molecular FormulaC14H14O3S
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Purity>98% (HPLC)
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SolubilityDMSO:25mg/mL(95.3 mM)
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SMILESCOCCSC1=C(C)C(=O)c2ccccc2C1=O
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Chemical Name2-[(2-Methoxyethyl)thio]-3-methyl-14-naphthalenedione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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