VK3-OCH3

CAS No. 255906-59-3

VK3-OCH3( 2-[(2-Methoxy)ethylthio]-3-methyl-14-na )

Catalog No. M20174 CAS No. 255906-59-3

2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 81 In Stock
10MG 113 In Stock
25MG 200 In Stock
50MG 291 In Stock
100MG 416 In Stock
200MG 588 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    VK3-OCH3
  • Note
    Research use only, not for human use.
  • Brief Description
    2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
  • Description
    2-[(2-Methoxy)ethylthio]-3-methyl-14-na is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
  • In Vitro
    VK3-OCH3 (compound 5) shows cytotoxicity with IC50s of 2.43, 1.55, 10.69, 3.45, 26.24, 87.11 μM for IMR-32, LA-N-1, NB-39, SK-N-SH, HUVEC, HDF cells, respectively.VK3-OCH3 (1, 3, 10 μM) induces apoptosis and cell cycle arrest at G2/M phase in IMR-32 cells.VK3-OCH3 (0-48 h) increases the expression of HO-1 in 8~24 h, and Caveolin-1 in 48 h in IMR-32 and LA-N-1 cells.VK3-OCH3 (0-48 h) increases the expression of phospho-p38-MAPK and decreases the expression of p21 and clusterin.
  • In Vivo
    ——
  • Synonyms
    2-[(2-Methoxy)ethylthio]-3-methyl-14-na
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    255906-59-3
  • Formula Weight
    262.32
  • Molecular Formula
    C14H14O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25mg/mL(95.3 mM)
  • SMILES
    COCCSC1=C(C)C(=O)c2ccccc2C1=O
  • Chemical Name
    2-[(2-Methoxyethyl)thio]-3-methyl-14-naphthalenedione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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