NMDAR antagonist 1

CAS No. 2220162-06-9

NMDAR antagonist 1( —— )

Catalog No. M20173 CAS No. 2220162-06-9

NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 98 In Stock
10MG 155 In Stock
25MG 297 In Stock
50MG 416 In Stock
100MG 551 In Stock
200MG 728 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    NMDAR antagonist 1
  • Note
    Research use only, not for human use.
  • Brief Description
    NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.
  • Description
    NMDAR antagonist 1 is a potent and orally bioavailable NR2B-selective antagonist of NMDAR.
  • In Vitro
    NMDAR antagonist 1 (Compound 5q) exhibits excellent neuroprotective activity. NMDAR antagonist 1 can attenuate Ca2+ influx induced by NMDA.NMDAR antagonist 1 can suppress the NR2B up-regulation and increase p-ERK1/2 expression.NMDAR antagonist 1 inhibits SH-SY5Y cells with cell viabilities of 75.8%, 80.0%, 84.4%, and 78.6% at 0.1 μM 1 μM 10 μM 100 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2220162-06-9
  • Formula Weight
    414.3
  • Molecular Formula
    C20H20BrN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc2N=C3CCC(N3Cc2c1)C(=O)NCCc1ccc(O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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