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AMAROGENTIN
CAS No. 21018-84-8
AMAROGENTIN( —— )
Catalog No. M20171 CAS No. 21018-84-8
Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 49 | In Stock |
|
| 10MG | 77 | In Stock |
|
| 25MG | 155 | In Stock |
|
| 50MG | 212 | In Stock |
|
| 100MG | 299 | In Stock |
|
| 200MG | 454 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAMAROGENTIN
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NoteResearch use only, not for human use.
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Brief DescriptionAmarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis
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DescriptionAmarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis.
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In Vitro——
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In VivoAnimal Model:Carbon tetrachloride (HY-Y0298)-induced liver fibrosis mice modelDosage:100 mg/kg Administration:p.o.Result:Decreased hepatic α-SMA and TGF-β1 expression.Inhibited phosphorylation of JNK, ERK, and p38.
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetAMPK
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RecptorAMPK
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Research Area——
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Indication——
Chemical Information
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CAS Number21018-84-8
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Formula Weight586.54
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Molecular FormulaC29H30O13
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Purity>98% (HPLC)
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SolubilityDMSO:2 mg/mL?(3.4 mM)
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SMILES[H][C@@]12CCOC(=O)C1=CO[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1OC(=O)c1c(O)cc(O)cc1-c1cccc(O)c1)[C@@H]2C=C
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Chemical Name(11'-Biphenyl)-2-carboxylic acid 33'5-trihydroxy- 2-ester with 5-ethenyl-6-(beta-D-glucopyranosyloxy)-44a56-tetrahydro-1H3H-pyrano(34-c)pyran-1-one (4aS-(4aalpha5beta6alpha))-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shantanu S Khushboo B Durai S et al. The Bitter Barricading of Prostaglandin Biosynthesis Pathway: Understanding the Molecular Mechanism of Selective Cyclooxygenase-2 Inhibition by Amarogentin a Secoiridoid Glycoside from Swertia chirayita[J]. PLoS ONE 2014 9(3):e90637-.
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