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DDD107498 succinate

CAS No. 1469439-71-1

DDD107498 succinate( DDD498 | M 5717 | MMV121 )

Catalog No. M20156 CAS No. 1469439-71-1

DDD107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite. It targets translation elongation factor 2 (eEF2).

Purity : >98% (HPLC)

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Biological Information

Product Name

DDD107498 succinate
Note

Research use only, not for human use.
Brief Description

DDD107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite. It targets translation elongation factor 2 (eEF2).
Description

DDD107498 has a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite. It targets translation elongation factor 2 (eEF2).
In Vitro

——
In Vivo

——
Synonyms

DDD498 | M 5717 | MMV121
Pathway

Microbiology/Virology
Target

Parasite
Recptor

eEF2
Research Area

Others
Indication

Malaria

Chemical Information

CAS Number

1469439-71-1
Formula Weight

580.65
Molecular Formula

C31H37FN4O6
Purity

>98% (HPLC)
Solubility

DMSO: 120 mg/mL (206.66 mM)
SMILES

OC(=O)CCC(O)=O.Fc1ccc2nc(cc(C(=O)NCCN3CCCC3)c2c1)-c1ccc(CN2CCOCC2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Baraga?a B et al. A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature. 2015 Jun 18;522(7556):315-20.

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