TH34

CAS No. 2196203-96-8

TH34( —— )

Catalog No. M20117 CAS No. 2196203-96-8

TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 93 In Stock
5MG 85 In Stock
10MG 122 In Stock
25MG 258 In Stock
50MG 407 In Stock
100MG 555 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TH34
  • Note
    Research use only, not for human use.
  • Brief Description
    TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.
  • Description
    TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC6| HDAC8| HDAC10
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2196203-96-8
  • Formula Weight
    256.3
  • Molecular Formula
    C15H16N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 80 mg/mL (312.13 mM);Water: Insoluble
  • SMILES
    Cc1ccc(cc1NCc1ccccc1)C(=O)NO
  • Chemical Name
    3-(benzylamino)-N-hydroxy-4-methylbenzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kolbinger FR et al. The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines. Arch Toxicol. 2018 Aug;92(8):2649-2664.
molnova catalog
related products
  • BRD 8430

    BRD 8430 is a potent, selective class I HDAC inhibitor (HDAC1>2 >3) with IC50 of 69 nM/560/1300 nM for HDAC1/2/3, respectively.

  • Valproic acid sodium...

    A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.

  • HDAC8-IN-22d

    HDAC8-IN-22d is a potent, selective HDAC8 inhibitor with IC50 of 27.2 nM.