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All trans-Retinal
CAS No. 116-31-4
All trans-Retinal( Retinaldehyde | Vitamin A aldehyde )
Catalog No. M19986 CAS No. 116-31-4
All-trans-retinal is a one of the major vitamin A metabolites in the retina. In physiological conditions all-trans-RAL is regenerated to the visual chromophore 11-cis-retinal.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 29 | In Stock |
|
| 50MG | 37 | In Stock |
|
| 100MG | 52 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 105 | In Stock |
|
| 1G | 160 | In Stock |
|
Biological Information
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Product NameAll trans-Retinal
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NoteResearch use only, not for human use.
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Brief DescriptionAll-trans-retinal is a one of the major vitamin A metabolites in the retina. In physiological conditions all-trans-RAL is regenerated to the visual chromophore 11-cis-retinal.
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DescriptionAll-trans-retinal is a one of the major vitamin A metabolites in the retina. In physiological conditions all-trans-RAL is regenerated to the visual chromophore 11-cis-retinal.
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In VitroCell Viability AssayCell Line:ARPE-19 cells Concentration:10 μM, 20 μM, 30 μM Incubation Time:16 h Result:Displayed a dose-dependent toxicity which included the morphological disruption of ARPE-19 cells.Western Blot Analysis Cell Line:ARPE-19 cells Concentration:10 μM, 30 μM Incubation Time:30 min Result:The phosphorylation of p53 at Ser 46 were detected prior to Bax activation in ARPE-19 cells.
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In Vivo——
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SynonymsRetinaldehyde | Vitamin A aldehyde
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number116-31-4
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Formula Weight284.44
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Molecular FormulaC20H28O
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Purity>98% (HPLC)
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SolubilityDMSO: 50 mg/mL;Ethanol: 25 mg/mL
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SMILESCC(\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C)=C/C=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sawada O et al. All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis. Exp Eye Res. 2014 Jun;123:27-36.
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