3-Methyladipic acid

CAS No. 3058-01-3

3-Methyladipic acid( —— )

Catalog No. M19985 CAS No. 3058-01-3

3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3-Methyladipic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation.
  • Description
    3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation and so the w-oxidation pathway is the only metabolic pathway available for phytanic acid degradation. This pathway produces 3-methyladipic acid as the final metabolite which is excreted in the urine.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3058-01-3
  • Formula Weight
    160.17
  • Molecular Formula
    C7H12O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:200 mM
  • SMILES
    CC(CCC(O)=O)CC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wierzbicki AS et al. Refsum's disease: a peroxisomal disorder affecting phytanic acid alpha-oxidation. J Neurochem. 2002 Mar;80(5):727-35.
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