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Glycodeoxycholic acid sodium salt
CAS No. 16409-34-0
Glycodeoxycholic acid sodium salt( Glycodeoxycholate Sodium | Sodium glycyldeoxycholate | Sodium glycodeoxycholate )
Catalog No. M19980 CAS No. 16409-34-0
Glycodeoxycholic Acid induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 29 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGlycodeoxycholic acid sodium salt
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NoteResearch use only, not for human use.
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Brief DescriptionGlycodeoxycholic Acid induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment.
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DescriptionGlycodeoxycholic Acid induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment.
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In VitroCell Cytotoxicity Assay Cell Line:Caco-2 cells Concentration:1 mM, 1.5 mM, 2 mM, 2.5mM, 3mM, 5mM Incubation Time:2h Result:Showed cytotoxic with IC50 of 2 mM.
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In Vivo——
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SynonymsGlycodeoxycholate Sodium | Sodium glycyldeoxycholate | Sodium glycodeoxycholate
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number16409-34-0
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Formula Weight471.61
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Molecular FormulaC26H42NNaO5
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Purity>98% (HPLC)
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SolubilityDMSO:199.3 mM
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SMILES[Na+].C[C@H](CCC(=O)NCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kwo P et al. Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes. Am J Physiol. 1995 Apr;268(4 Pt 1):G613-21.
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