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AZ876
CAS No. 898800-26-5
AZ876( —— )
Catalog No. M19966 CAS No. 898800-26-5
AZ876 is a potent highly selective LXR agonist with Ki/EC50 of 7/6 nM and 11/73 nM for hLXRα and hLXRβ respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 78 | In Stock |
|
| 10MG | 120 | In Stock |
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| 25MG | 157 | In Stock |
|
| 50MG | 193 | In Stock |
|
| 100MG | 343 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZ876
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NoteResearch use only, not for human use.
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Brief DescriptionAZ876 is a potent highly selective LXR agonist with Ki/EC50 of 7/6 nM and 11/73 nM for hLXRα and hLXRβ respectively.
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DescriptionAZ876 is a potent highly selective LXR agonist with Ki/EC50 of 7/6 nM and 11/73 nM for hLXRα and hLXRβ respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorLXR
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Research Area——
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Indication——
Chemical Information
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CAS Number898800-26-5
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Formula Weight439.57
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Molecular FormulaC24H29N3O3S
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Purity>98% (HPLC)
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SolubilityDMSO: 2.5 mg/mL
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SMILESCC(C)(C)N1C(=O)C(Nc2ccc(cc2)N2CCCCC2)=C(c2ccccc2)S1(=O)=O
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Chemical Name2-(11-Dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-3(2H)-isothiazolone 11-dioxide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.van der Hoorn J et al. Low dose of the liver X receptor agonist AZ876 reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels. Br J Pharmacol. 2011 Apr;162(7):1553-63.
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