Compound 3A

CAS No. 1822358-25-7

Compound 3A( —— )

Catalog No. M19944 CAS No. 1822358-25-7

Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 100 In Stock
5MG 92 In Stock
10MG 140 In Stock
25MG 217 In Stock
50MG 319 In Stock
100MG 462 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Compound 3A
  • Note
    Research use only, not for human use.
  • Brief Description
    Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.
  • Description
    Compound 3A can effectively inhibit the transcription of RNA polymerase I in the A375 malignant melanoma cell line but has no effect on polymerase II.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    RNA polymerase I
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1822358-25-7
  • Formula Weight
    356.42
  • Molecular Formula
    C21H20N6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C[C@H]1CN(C[C@@H](C)N1)c1ccc2cc(C#N)c3nc4ccccc4n3c2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chen L L Song J X Lu J H et al. Corynoxine a Natural Autophagy Enhancer Promotes the Clearance of Alpha-Synuclein via Akt/mTOR Pathway[J]. Journal of Neuroimmune Pharmacology 2014 9(3):380-387.
molnova catalog
related products
  • Puromycin dihydrochl...

    Puromycin 2hydrochloride is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.

  • Elinafide

    Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.

  • ML-60218

    ML-60218 (ML60218)?is a broad-spectrum, small molecule inhibitor of RNA polymerase (Pol) III with IC50 of 32 and 27 uM for Saccharomyces cerevisiae and human, respectively.