IRAK inhibitor 6

CAS No. 1042672-97-8

IRAK inhibitor 6( —— )

Catalog No. M19898 CAS No. 1042672-97-8

IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4 IC50: 160 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 120 In Stock
5MG 201 In Stock
10MG 294 In Stock
25MG 498 In Stock
50MG 709 In Stock
100MG 963 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
1 mL x 10 mM in DMSO 128 In Stock
5MG 117 In Stock
10MG 180 In Stock
25MG 297 In Stock
50MG 423 In Stock
100MG 576 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    IRAK inhibitor 6
  • Note
    Research use only, not for human use.
  • Brief Description
    IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4 IC50: 160 nM).
  • Description
    IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4 IC50: 160 nM).
  • In Vitro
    IRAK inhibitor 6 significantly improves potency against IRAK-4. Potency effects additive, IRAK inhibitor 6 is the most active compound among these compound tested.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Antiviral
  • Recptor
    IRAK-4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1042672-97-8
  • Formula Weight
    396.46
  • Molecular Formula
    C20H20N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mg/mL
  • SMILES
    COc1cc(ccc1NC(=O)c1csc(n1)-c1cccnc1)N1CCOCC1
  • Chemical Name
    N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Buckley G et al. IRAK-4 inhibitors. Part 1: a series of amides. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3211-4.
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