L-Kynurenine

CAS No. 2922-83-0

L-Kynurenine( (S)-Kynurenine )

Catalog No. M19725 CAS No. 2922-83-0

L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
25MG 29 In Stock
50MG 37 In Stock
100MG 52 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    L-Kynurenine
  • Note
    Research use only, not for human use.
  • Brief Description
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
  • Description
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (S)-Kynurenine
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite|AhR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2922-83-0
  • Formula Weight
    208.21
  • Molecular Formula
    C10H12N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (240.14 mM) Need ultrasonic;Water:4mg/mL(at 20°C);0.5M HCL:50mg/mL
  • SMILES
    N[C@@H](CC(=O)c1ccccc1N)C(O)=O
  • Chemical Name
    (S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kolho K L Pessia A Jaakkola T et al. Faecal and serum metabolomics in paediatric inflammatory bowel disease[J]. Journal of Crohns & Colitis 2017 11(3):321-334.
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