Aconitine( —— )

Catalog No. M19527 CAS No. 302-27-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Aconitine
Note

Research use only, not for human use.
Brief Description

Aconitine is a neurotoxin which activates tetrodotoxin-sensitive Na+ channelsinducing presynaptic depolarization and blocking the release of neurotransmitters.
Description

Aconitine is a neurotoxin which activates tetrodotoxin-sensitive Na+ channelsinducing presynaptic depolarization and blocking the release of neurotransmitters. Aconitine also blocks norepinephrine reuptake.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Sodium Channel
Recptor

Sodium Channel
Research Area

Inflammation/Immunology
Indication

Fever; Pain

CAS Number

302-27-2
Formula Weight

645.74
Molecular Formula

C34H47NO11
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

CCN1C[C@@]2([C@@H](C[C@@H]([C@@]34[C@@H]2[C@H]([C@@H](C31)[C@@]5([C@@H]6[C@H]4C[C@@]([C@@H]6OC(=O)C7=CC=CC=C7)([C@H]([C@@H]5O)OC)O)OC(=O)C)OC)OC)O)COC
Chemical Name

Aconitane-38131415-pentol 20-ethyl-1616-trimethoxy-4-(methoxymethyl)- 8-acetate 14-benzoate (1alpha3alpha6alpha14alpha15alpha16beta)-

1.Zhou YH et al. Int J Med Sci. 2013 Aug 1;10(9):1242-9.

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