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Betrixaban hydrochloride

CAS No. ——

Betrixaban hydrochloride( PRT054021 hydrochloride )

Catalog No. M19476 CAS No. ——

Betrixaban is a potent selective and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Betrixaban hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Betrixaban is a potent selective and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).
  • Description
    Betrixaban is a potent selective and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PRT054021 hydrochloride
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Factor Xa
  • Recptor
    Factor Xa
  • Research Area
    Cardiovascular Disease
  • Indication
    Venous thromboembolism

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    488.36
  • Molecular Formula
    C23H23Cl2N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 20 mg/mL (44.26 mM)
  • SMILES
    Cl.COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang P et al. Discovery of Betrixaban (PRT054021) N-(5-chloropyridin-2-yl)-2-(4-(NN-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide a highly potent selective and orally efficacious factor Xa inhibitor. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2179-85.
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