Lobetyolin

CAS No. 136085-37-5

Lobetyolin( Praeruptorin D )

Catalog No. M19431 CAS No. 136085-37-5

Lobetyolin is compound derived from Codonopsis pilosula with antioxidative effect.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 121 In Stock
5MG 109 In Stock
10MG 169 In Stock
25MG 282 In Stock
50MG 421 In Stock
100MG 620 In Stock
200MG 883 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Lobetyolin
  • Note
    Research use only, not for human use.
  • Brief Description
    Lobetyolin is compound derived from Codonopsis pilosula with antioxidative effect.
  • Description
    Lobetyolin is compound derived from Codonopsis pilosula with antioxidative effect.(In Vitro):Lobetyolin is derived from Codonopsis pilosula and has antioxidative effect. MUC5AC gene expression induced by phorbol 12-myristate 13-acetate (PMA) from NCI-H292 cells is inhibited by pretreatment with Lobetyolin, lobetyol or methyl linoleate. Lobetyolin does not affect PMA-induced MUC5AC production from NCI-H292 cells. The amounts of mucin in the cells of Lobetyolin-treated cultures are 100±25%, 487±33%, 524±38%, 411±24%, and 402±45% for control, 10 ng/mL of PMA alone, PMA plus Lobetyolin 1 μM, PMA plus Lobetyolin 10 μM, and PMA plus Lobetyolin 100 μM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Praeruptorin D
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    136085-37-5
  • Formula Weight
    396.43
  • Molecular Formula
    C20H28O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50.5 mM
  • SMILES
    C\C=C\C#CC#CC(O)C(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)\C=C\CCCO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yoon YP. et al. Effects of Lobetyolin Lobetyol and Methyl linoleate on Secretion Production and Gene Expression of MUC5AC Mucin from Airway Epithelial Cells. Tuberc Respir Dis (Seoul). 2014 Nov;77(5):203-8.
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