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Ondansetron
CAS No. 99614-02-5
Ondansetron( GRC50775 | SN307 )
Catalog No. M19306 CAS No. 99614-02-5
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 52 | In Stock |
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| 25MG | 44 | In Stock |
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| 100MG | 63 | In Stock |
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| 200MG | 93 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameOndansetron
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NoteResearch use only, not for human use.
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Brief DescriptionOndansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
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DescriptionThis medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.
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In Vitro——
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In VivoAnimal Model:NSCLC Patients Treated With Chemotherapy Dosage:8 mg Administration:Intraperitoneal Injection (i.p.)Result:Showed TD50 and LD50 doses with 3.7±0.6 mg/kg and 4.6±0.5 mg/kg, respectively.Animal Model:Male Swiss Mice with Colitis Dosage:2 mg/kg Administration:Intraperitoneal Injection (i.p.)Result:Showed dramatic reduction in MPO activity and tumor necrosis factor-alpha, interleukin-6 and interleukin-1 beta.
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SynonymsGRC50775 | SN307
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PathwayOthers
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TargetOther Targets
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Recptor5-HT3 receptor
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Research AreaCancer|Neurological Disease
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Indication——
Chemical Information
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CAS Number99614-02-5
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Formula Weight293.36
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Molecular FormulaC18H19N3O
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Purity>98% (HPLC)
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SolubilityH2O : < 0.1 mg/mL DMSO : < 1 mg/mL
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SMILESCC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C
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Chemical Name1, 2, 3, 9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1- yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Haj-Mirzaian A, et al. Eur J Pharmacol. 2016 Mar 19. pii: S0014-2999(16)30157-1.
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