Poliumoside( —— )

Catalog No. M19272 CAS No. 94079-81-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Poliumoside
Note

Research use only, not for human use.
Brief Description

Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM.
Description

Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase with IC50 values of 0.85 μM.Poliumoside has oxidant scavenging, antibacterial and hemostasis capacities, it can inhibit Biofilm-forming Staphylococcus aureus in mice.
In Vitro

Poliumoside inhibits AGE formation and RLAR, with IC50s of 19.69, and 8.47 μM, respectively.Poliumoside (5-30 μM; 3 h) inhibits AAPH-induced hemolysis of rat red blood cells in vitro.Poliumoside (12.5-100 μM; pretreated 2 h) inhibits the release of TNF-α and IL-6 in LPS-induced RAW 264.7?cells.
In Vivo

Poliumoside inhibits vessel dilation in larval zebrafish.
Synonyms

——
Pathway

Microbiology/Virology
Target

Antifungal
Recptor

Aldose reductase
Research Area

Metabolic Disease
Indication

——

CAS Number

94079-81-9
Formula Weight

770.73
Molecular Formula

C35H46O19
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (129.75 mM)
SMILES

Oc1ccc(cc1O)/C=C/C(=O)O[C@@H]5[C@@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)O[C@@H](OCCc3ccc(O)c(O)c3)[C@H](O)[C@H]5O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O
Chemical Name

——

1.Tai BH, et al.Total peroxynitrite scavenging capacity of phenylethanoid and flavonoid glycosides from the flowers of Buddleja officinalis.

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