Quinolinic acid

CAS No. 89-00-9

Quinolinic acid( —— )

Catalog No. M19233 CAS No. 89-00-9

Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 43 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G 28 In Stock

Biological Information

  • Product Name
    Quinolinic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
  • Description
    Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
  • In Vitro
    Quinolinic acid (0-50 mM; 24 hours) decreases the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM in N18D3 cells. Cell Viability Assay Cell Line:N18D3 cells, hybrid neuronal cell line obtained by fusion of dorsal root ganglions isolated from 4-week-old Balb/C mouse with the mouse neuroblastoma N18TG2 cells Concentration:0, 10, 20, 30, 40, 50 mM Incubation Time:24 hoursResult:There was a corresponding decrease in the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NMDA receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    89-00-9
  • Formula Weight
    173.17
  • Molecular Formula
    C10H7NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 33.33 mg/mL 199.44 mM
  • SMILES
    OC(=O)c1cccnc1C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lugohuitrón R, et al. Quinolinic acid: an endogenous neurotoxin with multiple targets.[J]. Oxidative Medicine and Cellular Longevity,2013,(2013-9-5), 2013, 2013:104024.
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