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PGD2-inhibitor
CAS No. 885066-67-1
PGD2-inhibitor( MDK66671 | MDK-66671 MDK 66671 )
Catalog No. M19229 CAS No. 885066-67-1
MDK66671 is a prostaglandin D2（PGD2) inhibitor. MDK66671 has CAS#885066-67-1, in which the last five digit was used in its name.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 162 | In Stock |
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| 5MG | 154 | In Stock |
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| 10MG | 259 | In Stock |
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| 25MG | 436 | In Stock |
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| 50MG | 630 | In Stock |
|
| 100MG | 896 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1795 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePGD2-inhibitor
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NoteResearch use only, not for human use.
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Brief DescriptionMDK66671 is a prostaglandin D2（PGD2) inhibitor. MDK66671 has CAS#885066-67-1, in which the last five digit was used in its name.
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DescriptionMDK66671 is a prostaglandin D2（PGD2) inhibitor. MDK66671 has CAS#885066-67-1, in which the last five digit was used in its name.
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In VitroProstaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists has been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically has been shown to inhibit the antigen-induced nasal congestion.
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In Vivo——
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SynonymsMDK66671 | MDK-66671 MDK 66671
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PathwayOthers
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TargetOther Targets
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RecptorPGD2(DP)
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Research Area——
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Indication——
Chemical Information
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CAS Number885066-67-1
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Formula Weight460.35
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Molecular FormulaC23H23Cl2N3O3
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 25 mg/mL; 54.31 mM
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SMILESCOc2nc(cc(NCCc1ccc(Cl)cc1Cl)n2)c3cccc(c3)C(C)(C)C(=O)O
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Chemical Name2-(3-(6-((2,4-dichlorophenethyl)amino)-2-methoxypyrimidin-4-yl)phenyl)-2-methylpropanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mu L, et al. Understanding DP receptor antagonism using a CoMSIA approach. Bioorg Med Chem Lett. 2011 Jan 1;21(1):66-75.
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