Notopterol

CAS No. 88206-46-6

Notopterol( Notopterol )

Catalog No. M19223 CAS No. 88206-46-6

Notopterol induces apoptosis and inhibits cell cycle-specific.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 44 In Stock
5MG 40 In Stock
10MG 56 In Stock
25MG 93 In Stock
50MG 137 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Notopterol
  • Note
    Research use only, not for human use.
  • Brief Description
    Notopterol induces apoptosis and inhibits cell cycle-specific.
  • Description
    Notopterol is an analgesic compound with anti-inflammatory action isolated from Notopterygium incisum Ting.
  • In Vitro
    notopterol (5, 10, 20, 40, 60 μM; for 48 hours) promotes cell apoptosis in a dose-dependent manner. notopterol (10, 20, 40, 60 and 80 μM; 24-120 hours) inhibits the proliferation of HL-60 cells in a concentration-dependent manner. Notopterol (5, 10, 20 and 40 μM; for 48 hours) induces G0/G1 phase arrest associated with cell-cycle proteins in HL-60 cells. Notopterol (5, 10, 20 and 40 μM; for 48 hours) increases the expression of Bax and decreased the expression of Bcl-2 and Mcl-1 in HL-60 cells after 48-hr treatment. Moreover, Notopterol also promotes the cleavage of caspase 9, caspase 3 and PARP.
  • In Vivo
    ——
  • Synonyms
    Notopterol
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    88206-46-6
  • Formula Weight
    354.4
  • Molecular Formula
    C21H22O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (282.17 mM)
  • SMILES
    CC(=CC(CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C)O)C
  • Chemical Name
    7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((5-hydroxy-3,7-dimethyl-2,6-octadienyl)oxy)-, (E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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