Astragaloside II

CAS No. 84676-89-1

Astragaloside II( Astrasieversianin VIII )

Catalog No. M19174 CAS No. 84676-89-1

Astragaloside II is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 46 In Stock
10MG 38 In Stock
25MG 79 In Stock
50MG 117 In Stock
100MG 175 In Stock
200MG 259 In Stock
500MG 444 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Astragaloside II
  • Note
    Research use only, not for human use.
  • Brief Description
    Astragaloside II is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy.
  • Description
    Astragaloside II is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, proliferation, and mineralization, through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Astrasieversianin VIII
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Smad1| Smad5| Smad8
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    84676-89-1
  • Formula Weight
    798.95
  • Molecular Formula
    C41H66O15
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL 120.92 mM; H2O : < 0.1 mg/mL
  • SMILES
    C(=O)(C)O[C@H]1[C@@H](OC[C@H]([C@@H]1O)O)O[C@H]1CC[C@]23C4(CC[C@]5([C@]([C@@H]4C[C@@H]([C@H]2C1(C)C)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)(C[C@@H]([C@@H]5[C@@]1(O[C@@H](CC1)C(C)(C)O)C)O)C)C)C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Huang C, et al. Reversal of P-glycoprotein-mediated multidrug resistance of human hepatic cancer cells by Astragaloside II. J Pharm Pharmacol. 2012 Dec;64(12):1741-50.
molnova catalog
related products
  • Penduletin

    Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Penduletin has strong activity in vitro against EV71 with low cytotoxicity.

  • RGD Trifluoroacetate

    RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.RGD Trifluoroacetate is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. There are 24 integrins binding to ECM molecules in a RGD dependent manner: α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1.

  • KKI-5 (TFA)

    KKI-5 (TFA) is a specific tissue kallikrein inhibitor.Kki-5 (TFA) can reduce breast cancer cell infiltration.