Astragalus polyphenols

Research use only, not for human use.

Astragalus polyphenols is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.

Astragalus polyphenols is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.

Western Blot Analysis Cell Line:RAW264.7 cells Concentration:5-80 μM Incubation Time:2 h Result:Reduced the phosphorylation level of ERK2, IκBα, IKKβ, and NF-κB p65 in a dosedependent manner.Attenuated LPS-induced nuclear translocation with a dose-dependent behavior.

Animal Model:Male ICR miceDosage:30-60 mg/kg Administration:i.p., daily, 7 days Result:Inhibited the production of proinflammatory cytokines induced by LPS, such as interleukin-1β, interleukin-6, and tumor necrosis factor-α.Prevented the LPS-induced enhancement of oxido-nitrosative stress in mouse hippocampus and prefrontal cortex.Prevented LPS-induced decreases in brain-derived neurotrophic factor levels in the hippocampus and prefrontal cortex.

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Angiogenesis

Adrenergic Receptor

Others

Others-Field

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82373-94-2

406.38

C20H22O9

>98% (HPLC)

DMSO : ≥ 35 mg/mL; 86.13 mM

[C@@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)Oc1c(/C=C/c2ccc(cc2)O)cc(cc1O)O

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(-20℃)

With Ice Pack

≥ 2 years