Dihydroergotoxine mesylate( Ergoloid Mesylates, Hydergine, Gerimal, CCK-179, CCK179 )

Catalog No. M19129 CAS No. 8067-24-1

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HNMR

HPLC

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Product Name

Dihydroergotoxine mesylate
Note

Research use only, not for human use.
Brief Description

It is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.
Description

Ergoloid Mesylates, also known as dihydroergotoxine mesylate, is a mixture of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine). Ergoloid mesylates is used as a treatment for dementia and Alzheimer disease. Ergoloid Mesylates stimulates dopaminergic and serotonergic receptors and blocks alpha-adrenoreceptors. Ergoloid Mesylates binds to the GABAA receptor Cl- channel, producing a reaction at the benzodiazepine site.
In Vitro

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In Vivo

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Synonyms

Ergoloid Mesylates, Hydergine, Gerimal, CCK-179, CCK179
Pathway

PI3K/Akt/mTOR signaling
Target

GSK-3
Recptor

Others
Research Area

Neurological Disease
Indication

——

CAS Number

8067-24-1
Formula Weight

673.82
Molecular Formula

C33H47N5O8S
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 31 mg/mL; 13.39 mM
SMILES

CS(O)(=O)=O.CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@@H]3C[C@H]4[C@@H](Cc5c[nH]c6cccc4c56)N(C)C3)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C
Chemical Name

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1.Abdul M, et al. Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer. Acta Oncol. 2008;47(8):1546-50.

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