Balsalazide( Balsalazide )

Catalog No. M19126 CAS No. 80573-04-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Balsalazide
Note

Research use only, not for human use.
Brief Description

Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
Description

Balsalazide is an anti-inflammatory agent for treatment of Inflammatory Bowel Disease.
In Vitro

——
In Vivo

At the endpoint, the protein production of MIP-1β, MCP-1, IL-6, and IL-10 in the colon tissues decrease in concordance with the plasma concentrations of the cytokines. The drug-treated groups reveal lower expression of p-STAT3 compared to the CAC group. In addition, BCL2 decreases and BAX increases markedly in the BSZ+VSL#3 group. Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug.
Synonyms

Balsalazide
Pathway

Others
Target

Other Targets
Recptor

Lipoxygenase
Research Area

Inflammation/Immunology
Indication

——

CAS Number

80573-04-2
Formula Weight

357.32
Molecular Formula

C17H15N3O6
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 41 mg/mL; 114.74 mM
SMILES

OC(=O)CCNC(=O)c1ccc(cc1)\N=N\c1ccc(O)c(c1)C(O)=O
Chemical Name

(E)-5-[[[-4-(2-Carboxyethyl)aminocarbonyl]phenyl]azo]-2-hydroxybenzoic acid

1. Kruis W, et al. Gut, 2001. 49(6): p. 783-789.

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