Isoliensinine( —— )

Catalog No. M18993 CAS No. 6817-41-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Isoliensinine
Note

Research use only, not for human use.
Brief Description

Isoliensinine, a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities.
Description

Isoliensinine, a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities. Isoliensinine possesses an anti-proliferative effect, which is related to the decrease of the overexpression of growth factors PDGF-beta, bFGF, proto-oncogene c-fos, c-myc and hsp7.
In Vitro

Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation.Isoliensinine exerts antiproliferative effect on CASMCs induced by phenylephrine, and its mechanisms are related to decrease the overexpression of growth factors (PDGF-beta, bFGF), protooncogene (c-fos, c-myc) and hsp70.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Antioxidant
Research Area

——
Indication

——

CAS Number

6817-41-0
Formula Weight

610.75
Molecular Formula

C37H42N2O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (81.87 mM)
SMILES

CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)O)O)OC
Chemical Name

——