4-Hydroxyquinoline( 4-Hydroxyquinoline | 4 Hydroxyquinoline | Kynurine | )

Catalog No. M18890 CAS No. 611-36-9

COA

Datasheet

HNMR

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MSDS

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Product Name

4-Hydroxyquinoline
Note

Research use only, not for human use.
Brief Description

4-Hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity.
Description

4-Hydroxyquinoline is a quinolone compound which forms the core moiety of antibacterials.
In Vitro

4-Quinolone (Kynurine) promotes tumor cell survival and motility by suppressing antitumor immune responses through AhR in an autocrine/paracrine fashion. This system is particularly active in human brain tumors where the activation of AhR enhances the expression of TDO producing more kynurine and kynurinic acid. In the healthy human brain, very low levels of TDO exist, whereas, in human brain tumors, the TDO protein levels increase with malignancy.
In Vivo

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Synonyms

4-Hydroxyquinoline | 4 Hydroxyquinoline | Kynurine |
Pathway

Others
Target

Antioxidant
Recptor

Antibacterial
Research Area

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Indication

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1. Criado S, et al. Journal of Photochemistry & Photobiology B Biology, 2003, 71(1):19-25.

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