Thiocolchicoside( —— )

Catalog No. M18874 CAS No. 602-41-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Thiocolchicoside
Note

Research use only, not for human use.
Brief Description

Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects.
Description

Thiocolchicoside (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine receptor antagonist with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.(In Vitro):Thiocolchicoside (0.001, 0.1, 1, 10, 100 μM) reduces the amplitude of eIPSCs in a concentration-dependent manner with this effect being significant at 0.1 μM and maximal at 10 μM.
In Vitro

Thiocolchicoside (0.001, 0.1, 1, 10, 100 μM) reduces the amplitude of eIPSCs in a concentration-dependent manner with this effect being significant at 0.1 μM and maximal at 10 μM.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Others-Field
Indication

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CAS Number

602-41-5
Formula Weight

563.61
Molecular Formula

C27H33NO10S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (443.56 mM)
SMILES

CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC4C(C(C(C(O4)CO)O)O)O
Chemical Name

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