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Licochalcone B
CAS No. 58749-23-8
Licochalcone B( Licochalcone B | Licochalcone-B )
Catalog No. M18855 CAS No. 58749-23-8
Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 136 | In Stock |
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| 5MG | 113 | In Stock |
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| 10MG | 188 | In Stock |
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| 25MG | 330 | In Stock |
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| 50MG | 479 | In Stock |
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| 100MG | 695 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLicochalcone B
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NoteResearch use only, not for human use.
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Brief DescriptionLicochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model.
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DescriptionLicochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. LCB and Licochalcone D(LCD) significantly reduced the LPS-induced production of NO, TNFalpha and MCP-1. A novel LCB derivative compound: (E)-3-(3, 4-dihydroxy-2-methoxyphenyl)-1-(2, 4-dihydroxyphenyl)prop-2-en-1-one inhibits inflammatory reactions in macrophages and protects mice from endotoxin shock.
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In VitroWestern Blot Analysis Cell Line:RAW264.7 cells Concentration:10 μM Incubation Time:1 h Result:Inhibited the phosphorylation of NF-κB at serine 276 but not at serine 536.
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In VivoAnimal Model:Mice induced by CCl4 Dosage:1, 5, 25 mg/kg Administration:Oral gavage.Result:Elevated the levels of SOD and GSH, and reduced the GSSG levels.
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SynonymsLicochalcone B | Licochalcone-B
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number58749-23-8
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Formula Weight286.28
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Molecular FormulaC16H14O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (291.08 mM)
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SMILESCOC1=C(C=CC(=C1O)O)C=CC(=O)C2=CC=C(C=C2)O
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Chemical Name(E)-1-(3,4-dihydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Etimizol
Etimizol?was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain).?
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O-Acetyl-L-carnitine...
Acetyl-L-carnitine hydrochloride is a blood-brain permeable acetyl ester of the amino acid L-carnitine found in the body. Acetyl-L-carnitine hydrochloride is often used as a dietary supplement, and exibits anti-stress-related psychiatric disorders.
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Thioflavin T
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