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ML204

CAS No. 5465-86-1

ML204( —— )

Catalog No. M18778 CAS No. 5465-86-1

ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	29	In Stock
10MG	39	In Stock
25MG	65	In Stock
50MG	83	In Stock
100MG	129	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ML204
Note

Research use only, not for human use.
Brief Description

ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Description

ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
In Vitro

——
In Vivo

Animal Model:Nonfasted male C57BL/6 (2-3 months)Dosage:1?mg/kg Administration:Subcutaneous injection, twice a day, for 5 days (prior to LPS injection)Result:Induced mortality associated with increased hypothermia in mice with LPS-induced systemic inflammatory response.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

TRPC4| TRPC5
Research Area

Neurological Disease
Indication

——

Chemical Information

CAS Number

5465-86-1
Formula Weight

226.32
Molecular Formula

C15H18N2
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 37 mg/mL; 163.49 mM
SMILES

c12c(cccc1)c(cc(n2)N1CCCCC1)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Miller M, et al. J Biol Chem. 2011 Sep 23;286(38):33436-46.

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