Cart
sales@molnova.com
7-Amino-4-(trifluoromethyl)coumarin
CAS No. 53518-15-3
7-Amino-4-(trifluoromethyl)coumarin( AFC )
Catalog No. M18755 CAS No. 53518-15-3
7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 27 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name7-Amino-4-(trifluoromethyl)coumarin
-
NoteResearch use only, not for human use.
-
Brief Description7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.
-
Description7-Amino-4-(trifluoromethyl)coumarin is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a Galanin Receptor 2 (GALR2) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a galanin receptor 2 (GalR2) antagonist. 7-Amino-4-(trifluoromethyl)coumarin is a HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 inhibitor with the activity value of 21 uM.
-
In Vitro——
-
In Vivo——
-
SynonymsAFC
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number53518-15-3
-
Formula Weight229.15
-
Molecular FormulaC10H6F3NO2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (436.38 mM)
-
SMILESC1=CC2=C(C=C1N)OC(=O)C=C2C(F)(F)F
-
Chemical Name7-Amino-4-trifluoromethylcoumarin
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
ACT-389949
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes.
-
Curculigoside
Curculigoside can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disorders.
-
ATI-2341 TFA
ATI-2341 is an effective functionally selective allosteric agonist for the c-x-c chemokine receptor type 4 (CXCR4), which ACTS as a biased ligand in favor of G G G G G 1 activation instead of G G G G G 13.ATI-2341 activates the inhibitory heterotrimer G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.ATI-2341 is an effective mobilization agent for myeloid polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs).
