Glycyl-L-Histidyl-L-Lysine( —— )

Catalog No. M18652 CAS No. 49557-75-7

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HNMR

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Product Name

Glycyl-L-Histidyl-L-Lysine
Note

Research use only, not for human use.
Brief Description

Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production.
Description

Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production.
In Vitro

Glycyl-L-histidyl-L-lysine and its copper complexes and saccharomyces/copper ferment on secretion of pro-inflammatory IL-6 in normal human dermal fibroblasts NHDF cell line.Glycyl-L-histidyl-L-lysine and its copper complexes decreases TNF-α-dependent IL-6 secretion in fibroblasts.
In Vivo

Glycyl-L-histidyl-L-lysine (intraperitoneal injection; 1.5, 5, 50, 150, and 450 mg/kg; 10 times ) can stimulate mitotic activity of hepatocytes and dose-dependently suppresse immune reactivity.Glycyl-L-histidyl-L-lysine (intraperitoneal injection; 0.5, 5, and 50 μg/kg) can produce an anxiolytic effect in the elevated plus maze test.
Synonyms

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Pathway

Others
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Other Targets
Recptor

Others
Research Area

Inflammation/Immunology
Indication

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1.Naughton BA,etal.The influence of pancreatic hormones and diabetogenic procedures on erythropoietin production.J Surg Oncol. 1982 Oct;21(2):97-103.

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