Epicatechin( Epicatechin | (-)-Epicatechin | epi-Catechol | NSC 81161 )

Catalog No. M18641 CAS No. 490-46-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Epicatechin
Note

Research use only, not for human use.
Brief Description

(-)-Epicatechin is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
Description

Epicatechin is a flavan-3-ol, a type of natural phenol and antioxidant. It is a plant secondary metabolite. The name of the catechin chemical family derives from catechu, which is the tannic juice or boiled extract of Mimosa catechu (Acacia catechu L.f). l-Epicatechin can be found in cacao beans and was first called kakaool or cacao-ol. Maximilian Nierenstein was among those who proved the presence of catechin in cocoa beans in 1931.
In Vitro

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In Vivo

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Synonyms

Epicatechin | (-)-Epicatechin | epi-Catechol | NSC 81161
Pathway

MAPK/ERK Signaling
Target

p38 MAPK
Recptor

Others
Research Area

Others-Field
Indication

——

CAS Number

490-46-0
Formula Weight

290.28
Molecular Formula

C15H14O6
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 34 mg/mL; 117.13 mM
SMILES

C1[C@H]([C@H](Oc2cc(cc(c12)O)O)c1cc(c(cc1)O)O)O
Chemical Name

(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

1. Kiewning D, et al. Food Chem. 2013 Sep 1;140(1-2):99-104.

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