Isofraxidin
CAS No. 486-21-5
Isofraxidin( Isofraxidin | Phytodolor )
Catalog No. M18627 CAS No. 486-21-5
Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 30 | In Stock |
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| 10MG | 36 | In Stock |
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| 25MG | 67 | In Stock |
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| 50MG | 99 | In Stock |
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| 100MG | 146 | In Stock |
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| 200MG | 217 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIsofraxidin
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NoteResearch use only, not for human use.
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Brief DescriptionIsofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
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DescriptionIsofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
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In Vitro——
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In Vivo——
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SynonymsIsofraxidin | Phytodolor
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PathwayOthers
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TargetOther Targets
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Recptorp38|ERK
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number486-21-5
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Formula Weight222.19
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Molecular FormulaC11H10O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (1125.16 mM)
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SMILESCOC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
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Chemical Name7-Hydroxy-6,8-dimethoxychromen-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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RLX-33
RLX-33 is a potent and selective antagonist of relaxin family peptide 3 (RXFP3) that crosses the blood-brain barrier and also blocks relaxin 3-induced ERK1/2 phosphorylation.
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D-(-)-Penicillamine
(2S)-2-Amino-3-methyl-3-sulfanylbutanoic acid is the most characteristic degradation product of the penicillin antibiotics.
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Ocimene
Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.
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