Isofraxidin

CAS No. 486-21-5

Isofraxidin( Isofraxidin | Phytodolor )

Catalog No. M18627 CAS No. 486-21-5

Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 30 In Stock
10MG 36 In Stock
25MG 67 In Stock
50MG 99 In Stock
100MG 146 In Stock
200MG 217 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Isofraxidin
  • Note
    Research use only, not for human use.
  • Brief Description
    Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner.
  • Description
    Isofraxidin protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. Isofraxidin has a protective effect against LPS-induced ALI, and the protective effect of Isofraxidin seems to result from the inhibition of COX-2 protein expression in the lung, which regulates the production of PGE2. Isofraxidin possesses significant analgesic and anti-inflammatory activities that may be mediated through the regulation of pro-inflammatory cytokines, TNF-α and the phosphorylation of p38 and ERK1/2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Isofraxidin | Phytodolor
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    p38|ERK
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    486-21-5
  • Formula Weight
    222.19
  • Molecular Formula
    C11H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1125.16 mM)
  • SMILES
    COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
  • Chemical Name
    7-Hydroxy-6,8-dimethoxychromen-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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