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Dehydrocostus Lactone
CAS No. 477-43-0
Dehydrocostus Lactone( Dehydrocostus Lactone | (-)-Dehydrocostus lactone. )
Catalog No. M18596 CAS No. 477-43-0
Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
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| 5MG | 37 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 122 | In Stock |
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| 50MG | 198 | In Stock |
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| 100MG | 305 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 734 | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDehydrocostus Lactone
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NoteResearch use only, not for human use.
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Brief DescriptionDehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.
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DescriptionDehydrocostus Lactone is a natural sesquiterpene first isolated from costus root, which is used in traditional medicine. Dehydrocostus lactone, a natural sesquiterpene lactone, suppresses the biological characteristics of glioma, through inhibition of the NF-κB/COX-2 signaling pathway by targeting IKKβ. Dehydrocostus Lactone Suppresses Proliferation of Human Chronic Myeloid Leukemia Cells Through Bcr/Abl-JAK/STAT Signaling Pathways. Dehydrocostus Lactone Inhibits Proliferation, Antiapoptosis, and Invasion of Cervical Cancer Cells Through PI3K/Akt Signaling Pathway.
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In Vitro——
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In Vivo——
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SynonymsDehydrocostus Lactone | (-)-Dehydrocostus lactone.
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number477-43-0
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Formula Weight230.3
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Molecular FormulaC15H18O2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 62.5 mg/mL; 271.39 mM
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SMILESC=C1CC[C@@H]2[C@@H]([C@@H]3[C@H]1CCC3=C)OC(=O)C2=C
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Chemical Name(3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(3H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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GRP-60367
GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
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inS3-54-A26
inS3-54-A26, a novel inhibitor of the DNA-binding domain (DBD) of STAT3, suppresses tumor growth, metastasis and STAT3 target gene expression in vivo.
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β-CGRP, human TFA
β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and CRLR/RAMP2 cells.
