Home - Products - Angiogenesis - PDE - Resibufogenin

Resibufogenin

CAS No. 465-39-4

Resibufogenin( RBG | Bufotenine | Resibufogenin )

Catalog No. M18571 CAS No. 465-39-4

Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	111	In Stock
5MG	101	In Stock
10MG	155	In Stock
25MG	282	In Stock
50MG	461	In Stock
100MG	644	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Resibufogenin
Note

Research use only, not for human use.
Brief Description

Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system.
Description

Resibufogenin is a cytotoxic steroid isolated from the Chinese drug ChanSu. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .
In Vitro

——
In Vivo

——
Synonyms

RBG | Bufotenine | Resibufogenin
Pathway

Angiogenesis
Target

PDE
Recptor

Others
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

465-39-4
Formula Weight

384.51
Molecular Formula

C24H32O4
Purity

>98% (HPLC)
Solubility

DMSO : 100 mg/mL 260.07 mM
SMILES

CC12CCC(CC1CCC3C2CCC4(C35C(O5)CC4C6=COC(=O)C=C6)C)O
Chemical Name

14,15beta-Epoxy-3beta-hydroxy-5beta-bufa-20,22-dienolide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

MBCQ

MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.
Torbafylline

Torbafylline, a xanthine derivative, is a phosphodiesterase (PDE) inhibitor that attenuates burn-induced protein hydrolysis in rat skeletal muscle through activation of the PDE4/cAMP/EPAC/PI3K/Akt pathway.
cis-Tadalafil

cis-Tadalafil (cis-IC-351) is a potent PDE5 inhibitor with an IC50 value of 0.09 μM that can be used to study arterial hypertension.

Sign In Join Free