Home - Products - Others - Other Targets - Lasmiditan

Lasmiditan

CAS No. 439239-90-4

Lasmiditan( COL-144 | LY573144 )

Catalog No. M18554 CAS No. 439239-90-4

Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	92	In Stock
5MG	138	In Stock
10MG	239	In Stock
25MG	525	In Stock
50MG	957	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Lasmiditan
Note

Research use only, not for human use.
Brief Description

Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study.
Description

Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo.
In Vitro

——
In Vivo

——
Synonyms

COL-144 | LY573144
Pathway

Others
Target

Other Targets
Recptor

5-HT1F
Research Area

Neurological Disease
Indication

——

Chemical Information

CAS Number

439239-90-4
Formula Weight

377.14
Molecular Formula

C19H18F3N3O2
Purity

>98% (HPLC)
Solubility

——
SMILES

CN1CCC(CC1)C(=O)c1nc(ccc1)NC(=O)c1c(cc(cc1F)F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Nelson DL, et al. Cephalalgia. 2010 Oct;30(10):1159-69.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

NorA-IN-1

NorA-IN-1 is a NorA efflux inhibitor, which can be used to study overcoming multidrug resistance based on microbial efflux transporter proteins.
Ibuprofen diethylami...

Ibuprofen diethylaminoethyl ester (BF DEAE) has anti-inflammatory activity, acts as a local anaesthetic and can be used in the study of neurological disorders.
Thymocartin

Thymocartin (RGH 0206) is a fragment 32-35 of the naturally occurring thymic factor (thymopoietin).Thymocartin is used in the study of immunodeficiency diseases.

Sign In Join Free