Lasmiditan
CAS No. 439239-90-4
Lasmiditan( COL-144 | LY573144 )
Catalog No. M18554 CAS No. 439239-90-4
Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 92 | In Stock |
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| 5MG | 138 | In Stock |
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| 10MG | 239 | In Stock |
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| 25MG | 525 | In Stock |
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| 50MG | 957 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLasmiditan
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NoteResearch use only, not for human use.
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Brief DescriptionLasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study.
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DescriptionLasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo.
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In Vitro——
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In Vivo——
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SynonymsCOL-144 | LY573144
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PathwayOthers
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TargetOther Targets
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Recptor5-HT1F
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number439239-90-4
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Formula Weight377.14
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Molecular FormulaC19H18F3N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1CCC(CC1)C(=O)c1nc(ccc1)NC(=O)c1c(cc(cc1F)F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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26Rfa, Hypothalamic ...
This human neuropeptide of the RFamide peptide family with orexigenic activity may be also involved in the control of feeding behavior. The 26RFa gene is exclusively expressed in the ventromedial hypothalamic nucleus and in the lateral hypothalamic area. The primary structures of human, rat, and frog 26RFa exhibit ≈80% identity. Other data suggest also the potential role of the 26RFa peptide in the control of the gonadotropic axis.
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Apocarotenal
Apocarotenal (trans-β-apo-8'-carotenal) is a carotenoid found in spinach and citrus fruits. Apocarotenal is used in fat-based food (margarine sauces salad dressing) beverages dairy products and sweets.
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CB-5339
p97-IN-1 is a potent inhibitor of p97 with an IC 50 <30 nM .
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