(-)-Gallocatechin gallate

CAS No. 4233-96-9

(-)-Gallocatechin gallate( (-)-Gallocatechol gallate | CCRIS 9286 )

Catalog No. M18538 CAS No. 4233-96-9

(-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 In Stock
5MG 57 In Stock
10MG 86 In Stock
25MG 176 In Stock
50MG 259 In Stock
100MG 390 In Stock
200MG 370 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    (-)-Gallocatechin gallate
  • Note
    Research use only, not for human use.
  • Brief Description
    (-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.
  • Description
    (-)-Gallocatechol gallate is an HIV integrase inhibitor found in Camilla sinensis. It displays a wide variety of biological activities, including suppressing amyloid formation by islet amyloid polypeptide, preventing nematode hatching, and inhibiting osteoclast differentiation.
  • In Vitro
    The amount of (-)-Gallocatechin gallate does not differ in leaves of different stages, and the content is relatively low. (?)-gallocatechin gallate in combination with active catechins ((?)-epigallocatechin gallate) has synergistic effects on the induction of apoptosis and inhibition of cell growth for PC-9 cells. (?)-gallocatechin gallate shows inhibitory effect on α-Glucosidase and DPPH, with IC50s of 30.2 μM and 12.2 μg/mL.
  • In Vivo
    ——
  • Synonyms
    (-)-Gallocatechol gallate | CCRIS 9286
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4233-96-9
  • Formula Weight
    458.38
  • Molecular Formula
    C22H18O11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 150 mg/mL; 327.25 mM
  • SMILES
    C1[C@H]([C@@H](Oc2cc(cc(c12)O)O)c1cc(c(c(c1)O)O)O)OC(=O)c1cc(c(c(c1)O)O)O
  • Chemical Name
    (2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ko CH,et al. Effects of tea catechins, epigallocatechin, gallocatechin, and gallocatechin gallate, on bone metabolism. J Agric Food Chem. 2009 Aug 26;57(16):7293-7.
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