Glycitin( Glycitein-7-beta-O-glucoside | Glycitin | ZX-AFC000687 )

Catalog No. M18523 CAS No. 40246-10-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Glycitin
Note

Research use only, not for human use.
Brief Description

Glycitin, a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.
Description

Glycitin is a TAS2R agonist found in soy. It suppresses invasive activity of glioma cells, increases proliferation of mouse bone marrow stromal cells and osteoblasts, and inhibits adipocytic transdifferentiation of osteoblasts.
In Vitro

Cell Viability Assay Cell Line:Bone marrow stem cells (BMSCs) Concentration:0.01, 0.5, 1, 5 and 10 μM Incubation Time:7 days Result:Increased cell proliferation and promoted osteoblast formation from BMSCs.
In Vivo

Animal Model:BALB/c male mice (6-8 weeks old, 18-22 g weight) treated with LPS Dosage:5 mg/kg, 10 mg/kg and 20 mg/kg Administration:Intraperitoneal injection; three times (once every 8 h)Result:Obviously alleviated the lung injury induced by LPS.
Synonyms

Glycitein-7-beta-O-glucoside | Glycitin | ZX-AFC000687
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Others-Field
Indication

——

CAS Number

40246-10-4
Formula Weight

446.41
Molecular Formula

C22H22O10
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 38 mg/mL; 85.13 mM
SMILES

COc1c(cc2c(c1)c(=O)c(co2)c1ccc(cc1)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
Chemical Name

3-(4-hydroxyphenyl)-6-methoxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

1. Zang Y, Igarashi K, Yu C. Biosci Biotechnol Biochem. 2015;79(1):117-23.

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