Eleutheroside E( —— )

Catalog No. M18518 CAS No. 39432-56-9

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Datasheet

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Product Name

Eleutheroside E
Note

Research use only, not for human use.
Brief Description

Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities.
Description

Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the metabolism of drugs metabolized via CYP2C9 and CYP2E1. Eleutheroside E may treat rheumatoid arthritis or increase the toxicity of the drugs.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

NF-κB
Research Area

Inflammation/Immunology
Indication

——

CAS Number

39432-56-9
Formula Weight

742.73
Molecular Formula

C34H46O18
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 7.5 mg/mL; 10.10 mM
SMILES

COc1cc(cc(c1O[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)CO)O)O)O)OC)[C@@H]1[C@H]2CO[C@H]([C@H]2CO1)c1cc(c(c(c1)OC)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)OC
Chemical Name

——

1. Kil YS, et al. Arch Pharm Res. 2015 Nov;38(11):1921-5.

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