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Desvenlafaxine succinate hydrate

CAS No. 386750-22-7

Desvenlafaxine succinate hydrate( O-Desmethylvenlafaxine succinate hydrate )

Catalog No. M18506 CAS No. 386750-22-7

Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
50MG 28 In Stock
100MG 37 In Stock
200MG Get Quote In Stock
500MG 72 In Stock
1G 99 In Stock
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Biological Information

  • Product Name
    Desvenlafaxine succinate hydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
  • Description
    Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).(In Vitro):Desvenlafaxine succinate hydrate has the potential to inhibit CYP2D6, which could result in increased concentrations of drugs metabolized through this pathway. Desvenlafaxine succinate hydratealso induces CYP3A4, which could impact the metabolism of drugs metabolized via this enzyme.(In Vivo):Desvenlafaxine succinate hydrate (30 mg/kg, orally) significantly increases extracellular NE levels but had no effect on DA levels using microdialysis.
  • In Vitro
    Desvenlafaxine succinate hydrate has the potential to inhibit CYP2D6, which could result in increased concentrations of drugs metabolized through this pathway. Desvenlafaxine succinate hydratealso induces CYP3A4, which could impact the metabolism of drugs metabolized via this enzyme.
  • In Vivo
    Desvenlafaxine succinate hydrate (30 mg/kg, orally) significantly increases extracellular NE levels but had no effect on DA levels using microdialysis. Animal Model:Male rats.Dosage:30 mg/kg. Administration:Orally.Result:Significantly increased extracellular NE levels compared with baseline in the male rat hypothalamus but had no effect on DA levels using microdialysis.
  • Synonyms
    O-Desmethylvenlafaxine succinate hydrate
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    5-HT
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    386750-22-7
  • Formula Weight
    399.48
  • Molecular Formula
    C20H33NO7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 33 mg/mL; 82.61 mM
  • SMILES
    OC(=O)CCC(O)=O.CN(C)CC(C1=CC=C(O)C=C1)C1(O)CCCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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