AEBSF hydrochloride

Research use only, not for human use.

against HIV-1.

against HIV-1.

AEBSF inhibits the constitutive production of Aβ by directly inhibiting β-secretase in five different human cell lines, both neural and nonneural. AEBSF, as a serine protease inhibitor, inhibits the lysis of leukemic cells by human macrophages without inhibiting macrophage secretion of TNF-α and IL-1β. AEBSF also disturbs the growth of blastocysts on endometrial cells and inhibit the adhesion of HeLa cells on HUVECs by altering the protein secretion pattern.

AEBSF (76.8 mg/kg daily, i.p.) results in prolongation of the survival of mice that have been given a lethal T. gondii infection.AEBSF also reduces airway response and underlying inflammation in cockroach allergen-induced murine model.

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Proteasome/Ubiquitin

Tyrosinase

Serine Protease

Others-Field

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30827-99-7

239.69

C8H11ClFNO2S

>98% (HPLC)

DMSO : 100 mg/mL 417.21 mM

c1cc(ccc1CCN)S(=O)(=O)F.Cl

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(-20℃)

With Ice Pack

≥ 2 years