Protostemonine

Research use only, not for human use.

Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo.

Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro-inflammatory mediators, such as iNOS, NO and cytokines. Protostemonine shows strong nematicidal activity against Panagrellus redivevus, with the IC50 value of 0.10 uM.Protostemonine attenuates LPS/GalN-induced acute liver failure and upregulating HO-1 expression is implicated in its hepatoprotective activity. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration.

——

——

——

Others

Other Targets

Others

——

——

27495-40-5

417.5

C23H31NO6

>98% (HPLC)

——

CC1CC(OC1=O)C2CCC3N2CCCC4C3C(C(=C5C(=C(C(=O)O5)C)OC)O4)C

——

(-20℃)

With Ice Pack

≥ 2 years