Cart
sales@molnova.com
Linrodostat
CAS No. 1923833-60-6
Linrodostat( BMS-986205 | ONO-7701 )
Catalog No. M18180 CAS No. 1923833-60-6
BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
|
| 5MG | 49 | In Stock |
|
| 10MG | 75 | In Stock |
|
| 25MG | 154 | In Stock |
|
| 50MG | 253 | In Stock |
|
| 100MG | 406 | In Stock |
|
| 200MG | 600 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLinrodostat
-
NoteResearch use only, not for human use.
-
Brief DescriptionBMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
-
DescriptionBMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.(In Vitro):Linrodostat (0.01-100 μM; 72 hours; SKOV-3 and Jurkat clone E6-1 cells) treatment reduces the number of viable cells compared with the non-treated control. Linrodostat also induces cell death at much lower concentrations and its IC50 is 6.3 μM.
-
In VitroLinrodostat (0.01-100 μM; 72 hours; SKOV-3 and Jurkat clone E6-1 cells) treatment reduces the number of viable cells compared with the non-treated control. Linrodostat also induces cell death at much lower concentrations and its IC50 is 6.3 μM. Cell Viability Assay Cell Line:SKOV-3 and Jurkat clone E6-1 cells Concentration:0.01-100 μM Incubation Time:72 hours Result:Reduced the number of viable cells compared with the non-treated control and induced cell death at much lower concentrations.
-
In Vivo——
-
SynonymsBMS-986205 | ONO-7701
-
PathwayOthers
-
TargetOther Targets
-
RecptorIDO1
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1923833-60-6
-
Formula Weight410.91
-
Molecular FormulaC24H24ClFN2O
-
Purity>98% (HPLC)
-
SolubilityDMSO : 50 mg/mL 121.68 mM; H2O : < 0.1 mg/mL
-
SMILESClc1ccc(cc1)NC(=O)[C@H](C)[C@@H]2CC[C@@H](CC2)c3ccnc4ccc(F)cc34
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lillian L. Siu, et al. Cancer Res. 2017; 77 (13 Suppl): Abstract nr CT116.
molnova catalog
related products
-
Xphos
XPhos (2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
-
Sesamolin
Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production.
-
Insulin alpha-chain ...
This peptide is a fragment of the alpha-chain of insulin amino acids 1 to 13. The insulin a-chain epitope recognized by human T cells is posttranslationally modified.
