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Linrodostat
CAS No. 1923833-60-6
Linrodostat( BMS-986205 | ONO-7701 )
Catalog No. M18180 CAS No. 1923833-60-6
BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
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| 5MG | 49 | In Stock |
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| 10MG | 75 | In Stock |
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| 25MG | 154 | In Stock |
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| 50MG | 253 | In Stock |
|
| 100MG | 406 | In Stock |
|
| 200MG | 600 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLinrodostat
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
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DescriptionBMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.(In Vitro):Linrodostat (0.01-100 μM; 72 hours; SKOV-3 and Jurkat clone E6-1 cells) treatment reduces the number of viable cells compared with the non-treated control. Linrodostat also induces cell death at much lower concentrations and its IC50 is 6.3 μM.
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In VitroLinrodostat (0.01-100 μM; 72 hours; SKOV-3 and Jurkat clone E6-1 cells) treatment reduces the number of viable cells compared with the non-treated control. Linrodostat also induces cell death at much lower concentrations and its IC50 is 6.3 μM. Cell Viability Assay Cell Line:SKOV-3 and Jurkat clone E6-1 cells Concentration:0.01-100 μM Incubation Time:72 hours Result:Reduced the number of viable cells compared with the non-treated control and induced cell death at much lower concentrations.
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In Vivo——
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SynonymsBMS-986205 | ONO-7701
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PathwayOthers
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TargetOther Targets
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RecptorIDO1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1923833-60-6
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Formula Weight410.91
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Molecular FormulaC24H24ClFN2O
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Purity>98% (HPLC)
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SolubilityDMSO : 50 mg/mL 121.68 mM; H2O : < 0.1 mg/mL
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SMILESClc1ccc(cc1)NC(=O)[C@H](C)[C@@H]2CC[C@@H](CC2)c3ccnc4ccc(F)cc34
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lillian L. Siu, et al. Cancer Res. 2017; 77 (13 Suppl): Abstract nr CT116.
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